Multiple Myeloma
Multiple myeloma is a rare and aggressive blood cancer that affects the body's plasma cells. This section explores its complexities, impact, and treatment options.
Stages of Multiple Myeloma
Multiple myeloma is a type of cancer that affects plasma cells, a type of white blood cell found in the bone marrow. Plasma cells are responsible for producing antibodies, which help fight infection. In multiple myeloma, these cells become abnormal and multiply uncontrollably. This can lead to a buildup of abnormal plasma cells in the bone marrow, which can crowd out healthy cells and cause a variety of problems.
Multiple myeloma is often diagnosed in one of three stages:
Smoldering Myeloma
An early, asymptomatic stage of the disease with no organ damage or related symptoms.
Indolent Myeloma
A slow-growing form of the disease with minimal symptoms and no immediate need for treatment.
Active Myeloma
The most common and aggressive form, requiring immediate treatment to manage symptoms and disease progression.
Prognosis and Survival
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Early Diagnosis
Prompt detection and treatment can significantly improve 5-year survival rates. Myeloma is higher in populations over 65, however patients are diagnosed much younger.
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Advancements in Therapy
New treatments, including targeted therapies and immunotherapies, have steadily increased survival over the past decade.
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Personalized Care
Tailoring treatment plans to individual patient needs and genetic profiles can optimize outcomes.
While there is no cure for Multiple Myeloma, clinical trials have been proven effective in treating myeloma and prolonging life. Patients and caregivers should consult their care team for information.
Types of Immunoglobulins in Myeloma
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Immunoglobulin Types
Multiple myeloma is often characterized by an overproduction of a specific type of antibody called immunoglobulin. These immunoglobulins are classified as follows:
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IgA
IgA is found in bodily fluids like saliva, tears, and breast milk. It helps protect against infections in the respiratory and digestive systems.
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IgD
IgD is found on the surface of B cells and plays a role in activating the immune response.
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IgM
IgM is the first antibody produced during an infection and helps to activate the complement system.
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IgG
IgG is the most abundant type of antibody in the blood and provides long-term immunity.
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IgE
IgE is involved in allergic reactions and helps protect against parasites.
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Biclonal Myeloma
Biclonal myeloma is a rare subtype where two different types of immunoglobulins are overproduced simultaneously.
How Multiple Myeloma Affects the Body
- Myeloma creates lytic lesions (holes in the bones) throughout the skeletal system, which can lead to bone fractures.
- The disease can also affect the kidneys, causing kidney failure.
- Myeloma can also affect the lungs, leading to respiratory distress.
- The disease can also cause blood clotting issues.
- Myeloma causes **C.R.A.B.** symptoms, including **C**alcium elevation, **R**enal insufficiency, **A**nemia, and **B**one lesions.
Patients undergo chemotherapy treatments, stem cell transplants, and other medicinal and therapeutic management to fight the disease.
Our Mission at MyeCure Foundation
Fund Research
Supporting groundbreaking research to improve treatment options and ultimately find a cure for multiple myeloma.
Patient Advocacy
Providing resources, support, and education to empower multiple myeloma patients and their families.
Raise Awareness
Increasing public understanding of this rare and complex form of blood cancer to drive positive change. We do this by hosting educational forums, partnerships with similar organizations, patient and caregiver input, conferences, and more importantly by people like you spreading the word!
Community Outreach
Fostering a network of support and collaboration among patients, caregivers, and healthcare providers.
Join the "Card for the Cure" Discount Program
Discounts
The card provides exclusive discounts at participating businesses, making it easier for patients to access essential goods and services.
Donations
an automatic donation from every card sold goes directly to supporting myeloma patients and funding research through the MyeCure Foundation.
Community
The program fosters a sense of unity and support among myeloma patients, their families, and the wider community.
Click on the link to see how you can become a MyeCure Advocate
The Founder's Personal Connection to Multiple Myeloma
A Driving Force for Change
The founder of the MyeCure Foundation has a personal connection to the fight against multiple myeloma, as they themselves were diagnosed with the disease. This firsthand experience has fueled their passion and dedication to supporting patients, advancing research, and ultimately finding a cure for this complex and challenging form of cancer.